550 5.7.1 Unable to Relay Mail From Exchange Server
Outlook cannot handle outbound mail. One or more of the following appears in the
There is a known bug tracked in JRA-31238 - Exchange with authentication requires From address matches the authenticated user Resolved which has been verified to affect instances where the project level From address is configured to be different from the global SMTP From address in JIRA applications.
Your Exchange mail server is not configured to relay messages.
Open the Exchange System Manager
- Go in Administrative Groups -> Administrative group name -> Server -> Server name -> Protocols -> SMTP
- Right click on Default SMTP Virtual Server -> properties
- Access tab -> Relay button
- Select "only the list below" and add the domain and\or IPs of your server
For Exchange 2007, create a second receive connector for external addresses as described in How to Set Up SMTP Relay in Exchange 2007.
Check Microsoft's Exchange Archive as well.
Take a look at Microsoft's documentation on how to set up permissions for relaying messages in Exchange.
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