Symptoms

When an Excel, Word or PowerPoint document is downloaded via Google Chrome, Office 2010 refuses to open the file with the error message "The file is corrupt and cannot be opened."  Downloading with other browsers works without issue.

Cause

Office 2010 introduced a feature called Protected View, which prevents documents from being opened if they are determined to be from an unknown source. Unfortunately, this appears to designate files downloaded by Chrome as unknown.

Resolution

• Follow the steps in this Microsoft Answers Question